Coronaviruses pandemics: Can neutralizing antibodies help?
نویسندگان
چکیده
منابع مشابه
Rapid Generation of Human-Like Neutralizing Monoclonal Antibodies in Urgent Preparedness for Influenza Pandemics and Virulent Infectious Diseases
BACKGROUND The outbreaks of emerging infectious diseases caused by pathogens such as SARS coronavirus, H5N1, H1N1, and recently H7N9 influenza viruses, have been associated with significant mortality and morbidity in humans. Neutralizing antibodies from individuals who have recovered from an infection confer therapeutic protection to others infected with the same pathogen. However, survivors ma...
متن کاملThe heptide repeat 2 and upstream region of TGEV induces potent cross-neutralizing antibodies against group I coronaviruses.
The coronavirus heptide repeat (HR) region in the spike protein induces neutralizing antibodies that block the postfusion core formation and inhibit virus entry into target cells. The HR2 regions for coronaviruses of the same serogroup share high homology. We found that polyclonal antibodies derived from transmissible gastroenteritis coronavirus HR2 and upstream region were cross-reactive with ...
متن کاملGlycans Function as Anchors for Antibodies and Help Drive HIV Broadly Neutralizing Antibody Development.
Apex broadly neutralizing HIV antibodies (bnAbs) recognize glycans and protein surface close to the 3-fold axis of the envelope (Env) trimer and are among the most potent and broad Abs described. The evolution of apex bnAbs from one donor (CAP256) has been studied in detail and many Abs at different stages of maturation have been described. Using diverse engineering tools, we investigated the i...
متن کاملCan Inspirational Quotes Help the Recall of Abstract Vocabulary?
The present study investigates the potential impact of inspirational quotes on improving English abstract vocabulary recall. To achieve this, a multiple-choice Oxford Quick Placement Test (OQPT) of 60 items including vocabulary and grammar component was administered as the proficiency test to a sample of 63 second-semester male and female students aged 18 to 22, studying English Translation in ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Life Sciences
سال: 2020
ISSN: 0024-3205
DOI: 10.1016/j.lfs.2020.117836